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Future investigations should integrate longitudinal human cohorts with mechanistic animal studies colonized by smoker-derived microbiota, which may provide causal insight into how specific taxa or metabolites mediate disease trajectories

According to FAIFA data, the growth in the illicit cigarette trade has resulted in a shrinkage of FCV crop production in India by a sharp 40%, from 316 million kg per annum in 2013/14 to 189 million kg per annum in 2021/22